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GlaxoSmithKline Jean-Pierre Garnier (former COO SmithKline Beecham) and the non-executive chairman is Sir Richard Sykes (former chairman of Glaxo Wellcome) and current rector of Imperial College. GSK was formed in December 2000 by a merger between Glaxo Wellcome and SmithKline Beecham, both the product of mergers themselves, as recently as 1995 for Glaxo and Wellcome. GSK was actually incorporated in Decmber 1999 as part of the lengthy merger process. As a result of the mergers the company has certain minor businesses which are not strictly within its larger interests. In 2002 pharmaceutical sales accounted for £18 billion of GSK's total sales. Sales Sources: Pheeds [R=1,P=105],
Total Points: 205.
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February 2003 South Africa, Syria, India, Russia, Canada and in the USA, in around 600 cities in total. February 14, 2003 Four ex-Symbionese Liberation Army members are sentenced to prison for the 1975 murder of Myrna Opsahl during a bank robbery in Carmichael, California.[1] A very large demonstration was held in Melbourne to protest against the Australian government's support for the USA's policy on Iraq. Organisers estimated that 200,000 people came out on to the streets, while some news sources put the number at "up to 150,000". [1] UNMOVIC chief weapons inspectors Hans Blix and Mohamed ElBaradei presented a report to the United Sources: Pheeds [R=2,P=52],
Total Points: 152.
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Antidepressant or lack of motivation before mood starts to improve. Antidepressants can often cause side effects, and an inability to tolerate these is the most common cause of discontinuing the medication. Sexual dysfunction is a very common side effect. More recent drugs have fewer side effects, but many patients are reporting severe side effects when they try to stop taking some antidepressants, particularly paroxetine. Additionally, certain patients do not respond to antidepressant drugs. Like many psychiatric drugs, antidepressants were discovered by accident. The first antidepressants, imipramine a tricyclic and isoniazid a monoamine oxidase inhibitor (MAOI), were found in the 1950s and the Sources: Pheeds [R=3,P=35],
Total Points: 135.
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Anxiolytic Valium (diazepam)and Xanax (alprazolam). They are used to treat a wide variety of conditions/symptoms, and usually a first choice any time short term CNS sedation is needed. Longer term uses include severe anxiety and psychosis. There is a risk of withdrawal symptoms and rebound syndrome after only a few weeks. There is an added problem of the accumulation of drug metabolites and adverse effects. Certain herbs, such as St. John's Wort, have been used as anxiolytics, but little reliable evidence is available for efficacy. St. John's Wort is generally thought to be a mild selective serotonin reuptake inhibitor, or SSRI, like Sources: Pheeds [R=4,P=26],
Total Points: 126.
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Xanax can also have more severe side effects, such as blurred vision, slurred speech, and changes in normal behavior. The drug is habituating, and users develop a tolerance. Psychological dependence after several months of Xanax treatment is common. As a result, long-term Xanax treatment cannot be abruptly terminated, but must instead be slowly reduced in dosage over a course of weeks (as is the case with many drugs operating on neurotransmitters). For more long-term relief of anxiety, selective serotonin reuptake inhibitor medicines such as Paxil, Zoloft, or Prozac are often prescribed. In the United States, the sale of Xanax is regulated by Sources: Pheeds [R=5,P=21],
Total Points: 121.
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Selective serotonin reuptake inhibitor discontinuing their use is known to produce both somatic and psychological withdrawal symptoms, a phenomenon know 1000 n as "SSRI discontinuation syndrome" (Tamam & Ozpoyraz, 2002). Their effectiveness does not appear to be higher than tricyclic antidepressants which were the most commonly used class of antidepressants before the SSRIs. However, SSRIs have the important advantage that the toxic dose is high, and, therefore, they are much more difficult to use as a means to commit suicide. Many drugs in this class are familiar through advertising, including fluoxetine (trade name: Prozac®, Fontex®, Seromex®, 'Seronil®) paroxetine (trade name: Paxil®, Seroxat®, Optipar®) sertraline (trade name: Zoloft®) Sources: Pheeds [R=6,P=17],
Total Points: 117.
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Paroxetine Paroxetine Paroxetine (paroxetine hydrochloride) is the formal name for Paxil® (in the United States) or Seroxat® (in the UK). It was released onto the market in 1992 by the pharmaceutical company GlaxoSmithKline and has since become one of the most successful anti-depressants on the market. It is the second most prescribed anti-depressant in the UK. Paroxetine is Sources: Pheeds [R=7,P=15],
Total Points: 115.
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Premenstrual stress syndrome of abdominal bloating and cramping. Diagnosis of PMDD requires a persistence of symptoms for several menstrual cycles, and differentiation from major depression and anxiety disorders. Treatment usually begins with lifestyle modification. Reducing caffeine, sugar and sodium intake may help. Supplements of vitamin B6 and calcium carbonate have been shown to help reduce symptoms. Vitamin B6 should be taken in doses of 50 to 100 micrograms per day. Calcium carbonate should be taken in doses of 1200 milligrams a day. Exercise will help reduce depression and anxiety symptoms. Keeping a symptom diary will help cue sufferers to exacerbating and relieving strategies. Prescription Sources: Pheeds [R=8,P=13],
Total Points: 113.
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Psychoactive substance affect one's cognitive state. This inlcudes most (if not all) recreational drugs, as well as psychiatric medications and many other prescription drugs are psychoactive. Common psychoactive substances Stimulants Caffeine Nicotine Cocaine Amphetamine Hallucinogens LSD Mescaline Psilocybin Cannabis (also an anti-depressant) PCP MDMA ("Ecstasy") DMT GHB Narcotics Opiates Morphine Codeine Heroin Ethyl alcohol Sedatives Benzodiazepines (Valium etc) Ketamine Anti-depressants SSRIss Prozac Zoloft Paxil See also: Psychedelic, Ibogaine. Sources: Pheeds [R=9,P=11],
Total Points: 111.
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Obsessive-compulsive disorder are not rational, but feel bound to comply with them because otherwise they suffer from panic or irrational dread. Obsessions are ideas that the person cannot stop thinking about. These are often fears about getting a disease, getting hurt, or causing harm to someone. Compulsions refer to actions that the person performs, usually repeatedly, in an attempt to make the obsession go away. These are often cleansing or avoidance actions. A common aspect of OCD is magical thinking, where the sufferer believes that they will be punished for their thoughts or failure to perform their self-imposed rituals. Often rituals are created Sources: Pheeds [R=10,P=10],
Total Points: 110.
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List of antidepressants Anti-depressant drugs may be augmented in the treatment of depression or other mood disorders by non-antidepressant drugs (such as lithium carbonate) which have been shown to boost the antidepressant effect of a main antidepressant treatment. Table of contents showTocToggle("show","hide") 1 SSRIs or selective serotonin reuptake inhibitors 2 MAOIs or monoamine oxidase inhibitors 3 Tricyclics 4 Tetracyclics 5 Others SSRIs or selective serotonin reuptake inhibitors citalopram (Celexa®;, Cipramil®;) escitalopram oxalate (Cipralex®, Lexapro®) fluvoxamine maleate (Luvox®) paroxetine (Paxil®, Seroxat®, Aropax®) fluoxetine 517 (Prozac®) sertraline (Zoloft®, Lustral®) MAOIs or monoamine oxidase inhibitors phenelzine (Nardil®) tranylcypromine (Parnate®) Tricyclics amitriptyline (Elavil®, Endep®) clomipramine (Anafranil®) desipramine (Norpramin®, Pertofrane®) Sources: Pheeds [R=11,P=9],
Total Points: 109.
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List of psychiatric drugs Antabuse Aripiprazole Artane Asendin Ativan Atomoxetine HCl Aventyl B Bupropion Buspar Buspirone C Calcium Carbonate Calcium Carbimide Carbamazepine Carbolith Celexa Chlordiazepoxide Chlorpromazine Cibalith-S Citalopram Clomipramine Clonazepam Clozapine Clozaril Cylert D Dalmane Depakene Depakote Desipramine Desoxyn Desyrel Dexedrine Dextroamphetamine Dextrostat Diazapam Dilantin Disulfiram Divalproex Doxepin Duralith E Edronax Effexor Elavil Endep Epitol Eskalith Escitalopram Etrafon F Fluoxetine Fluphenazine Flurazepam Fluvoxamine H Halcion Haldol Haloperidol I Imipramine Imovane K Klonopin L Largactil Levoprome Lexapro Libritabs Librium Lithane Lithium Lithizine Lithobid Lithonate Lithotabs Lorazepam Loxapac Loxapine Loxitane Ludiomil Luvox M Maprotiline Mellaril Mesoridazine Methamphetamine Methotrimeprazine Methylphenidate Modecate Minitran N Nardil Navane Nefazodone Norpramine Nortriptyline Sources: Pheeds [R=12,P=8],
Total Points: 108.
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