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Viagra that many fake aphrodisiacs now call themselves "herbal Viagra" or are presented as blue tablets imitating the shape and colour of Pfizer's product. Pfizer's worldwide patents on sildenafil citrate will expire in 2011 - 2013. The UK patent held by Pfizer on the use of PDE5 inhibitors (see below) as treatment of impotence has been invalidated in 2000 because of obviousness; this decision was upheld on appeal in 2002. Chemistry Chemical name: 1-[4-ethoxy- 3-(6,7-dihydro- 1-methyl- 7-oxo- 3-propyl- 1H-pyrazolo [4,3-d]pyrimidin-5-yl) phenylsulfonyl]- 4-methylpiperazine citrate. Chemical formula: C22H30N6O4S.C6H8O7. Molecular weight: 666.7 Molecular structure (citrate group not shown): Mechanism of action Part of the physiological Sources: Pheeds [R=1,P=105],
Total Points: 205.
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Tadalafil Tadalafil Tadalafil (Cialis®) is a drug used to treat male erectile dysfunction (impotence), developed by the pharmaceutical company Eli Lilly and Company. The generic name for this compound is sildenafil citrate. The tablet are yellow and oval-shaped. Cialis's main selling points: It works for up to 36 hours after being swallowed and can be taken with or without food. It has the same mode of action as Viagra, and Levitra. Lilly, of Indianapolis, and ICOS, of Bothell, Washington, will sell Cialis in the United States for a wholesale price of $8.10 a pill. Cialis has a Sources: Pheeds [R=2,P=52],
Total Points: 152.
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