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Herpes simplex virus with HSV-2, that is where outbreaks occur. The terminology of herpes can be quite confusing; the two viruses are sometimes referred to by the sites they preferentially infect. Thus, HSV-1 can be called "oral herpes," (or sometimes "cold sores") and HSV-2 can be called "genital herpes." However, it is perfectly possible to have an HSV-1 infection of the genitals, or an HSV-2 infection of the oral area. Another factor adds to the confusion; herpes is also sometimes described by the site of the infection. Thus, a herpes infection located in the genital region may be called "genital herpes," and a herpes Sources: Pheeds [R=1,P=105],
Total Points: 205.
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Encephalitis defense mechanisms being activated to get rid of infection (brain swelling, small bleedings and cell death). Neurologic examination usually reveals a stiff neck due to the irritation of the meninges covering the brain. Examination of the cerebrospinal fluid obtained by a lumbar puncture procedure reveals increased amounts of proteins and white blood cells with normal glucose. A CT scan examination is performed to reveal possible complications of brain swelling, brain abscess or bleeding. Lumbar puncture procedure is performed only after the possibility of a prominent brain swelling is excluded by a CT scan examination. Treatment is usually symptomatic. Reliably tested specific Sources: Pheeds [R=2,P=52],
Total Points: 152.
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Antiviral drug Release of viral particles to infect new host cells. The best time to attack a virus is as early as possible in its life cycle. In a sense, this is exactly what vaccines do. Vaccines traditionally consist of a weakened or killed version of a pathogen, though more recently "subunit" vaccines have been devised that consist strictly of protein targets from the pathogen. They stimulate the immune system without doing serious harm to the host, and so when the real pathogen attacks the subject, the immune system responds to it quickly and blocks it. Vaccines have an excellent track record for Sources: Pheeds [R=3,P=35],
Total Points: 135.
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Chickenpox Chicken pox has a two week incubation period and is highly contagious by air transmission two days before symptoms appear. Therefore chicken pox spreads quickly through schools and other places of close contact. As the disease is more severe if contracted by an adult, parents have been known to ensure that their children became infected before adulthood. Later in life, virus remaining in the nerves can develop into the painful disease, shingles. A chicken pox vaccine is now available, and is now required in some countries for children to be admitted into elementary school. In addition, effective medications (e.g., acyclovir) are Sources: Pheeds [R=4,P=26],
Total Points: 126.
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Shingles or patch of raised dots on the side of the trunk or face. The rash develops into small, fluid-filled blisters which begin to dry out and crust over within several days. When the rash is at its peak, symptoms can range from mild itching to extreme and intense pain. Contact with a person with shingles may cause chickenpox (but not shingles) in someone who has never had chickenpox before. This rash is generally limited to one dermatome on the body, which explains its confined appearance. Treatment Treatment for shingles includes antiviral drugs, steroids, antidepressants, anticonvulsants, and topical agents. The severity and Sources: Pheeds [R=5,P=21],
Total Points: 121.
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Varicella-zoster virus or zoster sine herpete) and post-herpetic neuralgia. It belongs to the genus Varicellovirus and the subfamily Alphaherpesvirinae. It is closely related to the herpes simplex viruses, sharing much genome homology. 1d9 It is usually spherical and 150-200 nm in diameter. Its lipid envelope encloses the nucleocapsid of 162 capsomeres arranged in a hexagonal form. Its DNA is a single linear, double strand molecule, 125,000 nt long. The virus is very susceptible to disinfectants, notably sodium hypochlorite. Within the body it is combatted by a number of drugs including vidarabine, zoster immune globulin (ZIG), and acyclovir. A live-virus vaccine has been approved and Sources: Pheeds [R=6,P=17],
Total Points: 117.
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